Stay clear of using promethazine HCl and codeine phosphate oral Resolution in adolescents 12 to eighteen decades of age who have other hazard elements that could raise their sensitivity towards the respiratory depressant results of codeine.
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Meticulously measure the dose employing a Exclusive measuring system/spoon. Never make use of a family spoon as you might not get the correct dose.
Observe individuals with a historical past of seizure Diseases for worsened seizure Manage through promethazine HCl and codeine phosphate oral Alternative therapy.
If promethazine HCl and codeine phosphate oral Alternative is prescribed, watch these kinds of individuals intently, specially when initiating promethazine HCl and codeine phosphate oral Remedy and when promethazine HCl and codeine phosphate oral Answer is specified concomitantly with other medicine that depress respiration [see Warnings and Precautions (5.ten)].
The following adverse reactions have already been discovered through medical studies, from the literature, or through write-up-acceptance utilization of codeine and/or promethazine.
Because of the prospective for promethazine to reverse epinephrine’s vasopressor impact, epinephrine shouldn't be employed to deal with hypotension related with promethazine overdose.
Use caution when considering the use of promethazine HCl and codeine phosphate oral Remedy in people sixty five a long time of age or older.
In certain Girls, this takes place in a short time. Codeine and morphine go into your breast milk. A great deal of morphine may cause your child to die.
FDA Drug Protection Conversation: FDA demands labeling changes for prescription opioid cough and chilly medicines to limit their use to Older people 18 years and more mature
5.19 Neonatal Opioid Withdrawal Syndrome Promethazine HCl and codeine phosphate oral Resolution will not be proposed to be used in pregnant Gals. Extended usage of promethazine HCl and codeine phosphate oral Alternative during pregnancy can result in withdrawal within the neonate. Neonatal opioid withdrawal syndrome, compared with opioid withdrawal syndrome in Older people, may be life-threatening Otherwise regarded and dealt with, and involves administration check here As outlined by protocols formulated by neonatology gurus.
The approximated track record threat of key beginning defects and miscarriage for your indicated populace is unfamiliar. All pregnancies Have a very track record danger of birth defect, decline, or other adverse outcomes.
Inspite of its glorification in well-liked culture, drinking lean comes with a host of prospective Uncomfortable side effects and destructive results. There are actually several notable music artists, many of whom promoted or mentioned using lean of their tracks, who definitely have handed away as the result of an overdose involving the drug concoction.
As a result of risks of addiction, abuse, and misuse with opioids, even at advisable doses [see Warnings and Safety measures (five.one)], reserve promethazine HCl and codeine phosphate oral Answer for use in adult clients for whom the advantages of cough suppression are predicted to outweigh the challenges, As well as in whom an adequate evaluation of your etiology of the cough continues to be manufactured.